CASE OF THE MONTH- June 2025

  Dr. Prach Nichat & Dr. Swarnalata Gowrishankar

  Apollo Hospitals, Hyderabad

CLINICAL HISTORY & INVESTIGATIONS:

A 72-yr old male with retroviral disease (RVD) status was being evaluated for renal dysfunction. He was on regular treatment with TLD ( Tenofovir, Lamivudine, Dolutegravir) regimen for last 6 years. During routine follow up, serum creatinine was found to be elevated at 1.9 mg/dl and increased to 2.3 mg/dl over the next three months. Complete urine examination (at the time of biopsy) – Albumin 1+, RBCs – nil. 24-hour urine protein 300 mg/dl. 

Renal biopsy was performed and examined by light microscopy and immunofluorescence(IF).

The photomicrographs of the kidney biopsy are attached. 

IF study showed 2 glomeruli without any significant immune deposits.